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Remoxipride hydrochloride

CAS No. 73220-03-8

Remoxipride hydrochloride( Roxiam | (S)-Remoxipride Hydrochloride | Remoxipride Hydrochloride Anhydrous )

Catalog No. M27695 CAS No. 73220-03-8

Dopamine D2 receptor antagonist.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Remoxipride hydrochloride
  • Note
    Research use only, not for human use.
  • Brief Description
    Dopamine D2 receptor antagonist.
  • Description
    Dopamine D2 receptor antagonist.(In Vivo):In male Sprague-Dawley rats, Remoxipride hydrochloride (0.1-100 μM/kg; i.p.) blockes apomorphine-induced hyperactivity and dose-dependent blockades apomorphine-induced behaviors. In beagle dogs, Remoxipride hydrochloride (0.25-5 μM/kg; gavage) blockes apomorphine-induced vomiting.
  • In Vitro
    (S)-Remoxipride hydrochloride (1-100 μM; 20 min) shows binding efficiency with IC50s of ＞100, 1.57 and 42 μM for dopamine D1, dopamine D2 and α1-Adrenoccptor, respectively.
  • In Vivo
    (S)-Remoxipride hydrochloride (0.1-100 μM/kg; i.p. 60 min prior to apomorphine) blockades apomorphine-induced behaviors s in rats and vomiting in dogs.(S)-Remoxipride hydrochloride (0.1-10 mg/kg; i.p. 30 min prior to apomorphine) displaces [3H]spiperone from both striatal and extra-striatal areas.
  • Synonyms
    Roxiam | (S)-Remoxipride Hydrochloride | Remoxipride Hydrochloride Anhydrous
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    73220-03-8
  • Formula Weight
    407.73
  • Molecular Formula
    C16H24BrClN2O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.CCN1CCC[C@H]1CNC(=O)c1c(OC)ccc(Br)c1OC
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Richard W. Watkins, et al. Evaluation of cinnamamide as an avian repellent: Determination of a dose—response curve.
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